Feb 3, 2022Liked by Dr. Colleen Huber

The goal is very simple:







Expand full comment

Thank You, Dr. Huber, for this refined and to-the-point presentation, point and counterpoint.

John Day MD

Expand full comment

You're missing another outcome: still pregnant. Note that the study was performed prior to March 31, which means the vast majority of the 1st and 2nd trimester patients would not have completed their pregnancies yet. That's why the live birth rate is so low. So now, it is not true that 90% of pregnancies will end in miscarriage or stillborn if the vaccine is taken in the 1st or 2nd trimester; it is just that this study is too early to draw final conclusions.

Expand full comment

Thank you for sharing this. This is definitely concerning, but after looking over the study itself it seems to be lacking enough data to draw the extreme conclusion you reached. The authors do seem to downplay the severity of these results, but the small sample size and reliance on self reporting makes this study lackluster in my eyes.

Expand full comment

Hi Colleen, it would be worth addressing for us the claims of the study conclusion in footnote 1 which say that the overall SAB rate was about the same as the overall SAB rate in the normal population, as well as the more recent CDC study with a larger sample size which drew the same conclusion, though from their Figure 1 I see opportunities to manipulate conclusions about the data e.g. potentially too short a time between receipt of the vaccine and the 20 week mark.

I followed your logic and I believe you are correct, and I don't know how the authors of the published study do not see what you're seeing - they're essentially diluting the SAB counts with a larger number of third-trimester reports, which are apparently much lower risk for SAB. This seems like an attempt to hide the numbers you're seeing here.

One minor correction - in your table you show 700 live births plus one still birth for women vaccinated in the third trimester (total 701), whereas the original paper says there were a total of 700 women who were vaccinated in the third trimester (total 700 - including the one stillbirth.)

Expand full comment

un freaking believable

Expand full comment

The letter pointing out the error and the author’s response is here - https://www.nejm.org/doi/full/10.1056/NEJMc2113516?query=recirc_curatedRelated_article

Expand full comment