Vaccines target a small portion of the entire human immune system and often lag behind mutations of microbes. Yet vaccines have dazzled humans for centuries.
Love your writing! It's powerful, well-researched and insightful! What's been missing since the beginning is the discussion on how NK Cells another immune defense mechanisms are inhibited by chronic stress/traumatic stress. With the lockdowns and other restrictions, they have promoted an environment of powerlessness and helplessness, which increase hyper-arousal and freeze response
Thank you for this lesson in immunology—the principles of which seem to have been “forgotten” (rewritten) thanks to the Orwellian redefinitions that have occurred over the past 20 months.
It’s helpful to get a better understanding of *why* vitamin D is so effective in the battle against infections.
I suspect inducing autophagy through intermittent fasting (best combined with a low-carb, high-fat diet like keto, which makes the practice easy due to the satiating fat) ramps up macrophage activity and helps build an even stronger immune system (https://pubmed.ncbi.nlm.nih.gov/31892110/). I wonder if it would help those who have been injected fend off some of the adverse effects of the spike proteins and toxins?
Thank you. I think the reason for vitamin D need relates more to our history. Until recent generations who take medical advice from TV, we humans, as other species, were not afraid of sun exposure and got plenty of it. It is simply necessary for good health, and it is a self-defeating practice to try to do without it. Go back several generations, and we're all descended from farmers, fishermen, builders. How many of those died of skin cancers? Not widely observed in that distant past.
Good report. Thanks! Last year I heard anecdotal reports that indicated no one with vitamin D above about 40 had been intubated or even in ICU or some such. Do you know if that has ever been quantified? And that was when everyone was ordered to stay indoors, missing the natural production from sunshine. And the apparent higher morbidity of dark skinned people seemed to mystify authorities, so it was hushed. Low D seemed a likely culprit. I'm guessing most people don't know their number. My own beloved doc sent me a report every year that listed numbers for the factors he tested, except D, which he reported as "normal." I had to ask for the actual lab report every year to get the real number, and found the threshold for normal is lower, low 20s I think. A lot of standard ranges are way lower than what we should want, certainly for D.
Yes, many studies correlated higher vitamin D levels with lower incidence of COVID and better outcomes in COVID patients. Here's a helpful site that's updated frequently. https://c19vitamind.com/
Amazing. Thanks. 130 studies showing vit D benefits and our corrupt medical industry ignores it. I doubt most of the casualties were even tested. There seems to be pretty clear correlation of outcomes vs D.
I've seen estimates that 1000 IU raises D about 10. Apparently there's a saturation level, else yours should be about 140, which I'm guessing it's not. The studies you provided indicate about 55 is the optimum for general infection, and seems to make covid infection low probability.
I get tested twice a year and I range 50-75 with 4000 IU. I'm in a sunny southern latitude too, but my sun exposure is mostly walking to and from my car. I'm an astronomy hobbyist, but I don't think I get much D from starlight. Cancer concerns probably discourage a lot of people from too much sun exposure. But it really doesn't take a lot of sun to get a normal dose. Sunlight also damages DNA which decreases longevity. Lots of mysteries remain, but there are likely optimum balances yet to be discovered. I'm hoping objective measurements will provide me with data that will maximize my own lifestyle. Working so far.
Yes, yours is likely a more appropriate dose for the general population. Cancer is such a difficult hurdle to overcome, that we in my medical practice go further in dosing. I say we, although I never had cancer (where's some wood I can knock on), but I do the equipoise thing along with the patients.
I assume your equipoise reference is seeking some sort of equilibrium, not the steroid. I've read we can't really overdose, but it seems likely there's a saturation point somewhere. I've heard healthy skin can produce up to 25,000 per day. Maybe that's for surfers or nudists? Or our evolutionary ancestors? Maybe we were designed for higher levels than we typically see these days. I'm wondering if I'm a slacker for accepting readings in the 50s, with "only" 4000 IU supplement.
I saw this article and didn't have time to read it when you published it, but I came back to it and am glad I did. I think I just got more information on the immune system in the last fifteen minutes than anyone has provided me in a year. Thank you!
Great article - very informative. Do you have any views on the Novavax vaccine? We are about to get it in Australia where I am located. Do you think it will have a similar potential for heart damage or is likely to be safer? It would be great to get your thoughts.
Yes - I agree but in my state it looks like I won’t be able to go into shops for 12 months and potentially not work unless I get one of the vaccines. I would prefer to get none of them and I really resent it being forced upon me but I may have to get it - was hoping novavax was a less harmful option?
My family chose to uproot and move across the US a few decades ago for the main reason that we are a non-vaccinating lineage, and vax exemptions are stronger in Arizona than elsewhere in the US. I would definitely do it again if I had to. So I'm probably not the best person to ask that particular question.
Love your writing! It's powerful, well-researched and insightful! What's been missing since the beginning is the discussion on how NK Cells another immune defense mechanisms are inhibited by chronic stress/traumatic stress. With the lockdowns and other restrictions, they have promoted an environment of powerlessness and helplessness, which increase hyper-arousal and freeze response
Exacerbated even further by the vilification of the unvaccinated.
Scapegoating cuz people waking up n might ask too many questions 😂
Thank you for this lesson in immunology—the principles of which seem to have been “forgotten” (rewritten) thanks to the Orwellian redefinitions that have occurred over the past 20 months.
It’s helpful to get a better understanding of *why* vitamin D is so effective in the battle against infections.
I suspect inducing autophagy through intermittent fasting (best combined with a low-carb, high-fat diet like keto, which makes the practice easy due to the satiating fat) ramps up macrophage activity and helps build an even stronger immune system (https://pubmed.ncbi.nlm.nih.gov/31892110/). I wonder if it would help those who have been injected fend off some of the adverse effects of the spike proteins and toxins?
BTW, I linked to your excellent overview of the data on ivermectin in my last piece (https://margaretannaalice.substack.com/p/letter-to-a-scientifically-minded) if you didn’t see it :-)
Thank you. I think the reason for vitamin D need relates more to our history. Until recent generations who take medical advice from TV, we humans, as other species, were not afraid of sun exposure and got plenty of it. It is simply necessary for good health, and it is a self-defeating practice to try to do without it. Go back several generations, and we're all descended from farmers, fishermen, builders. How many of those died of skin cancers? Not widely observed in that distant past.
Good report. Thanks! Last year I heard anecdotal reports that indicated no one with vitamin D above about 40 had been intubated or even in ICU or some such. Do you know if that has ever been quantified? And that was when everyone was ordered to stay indoors, missing the natural production from sunshine. And the apparent higher morbidity of dark skinned people seemed to mystify authorities, so it was hushed. Low D seemed a likely culprit. I'm guessing most people don't know their number. My own beloved doc sent me a report every year that listed numbers for the factors he tested, except D, which he reported as "normal." I had to ask for the actual lab report every year to get the real number, and found the threshold for normal is lower, low 20s I think. A lot of standard ranges are way lower than what we should want, certainly for D.
Yes, many studies correlated higher vitamin D levels with lower incidence of COVID and better outcomes in COVID patients. Here's a helpful site that's updated frequently. https://c19vitamind.com/
Amazing. Thanks. 130 studies showing vit D benefits and our corrupt medical industry ignores it. I doubt most of the casualties were even tested. There seems to be pretty clear correlation of outcomes vs D.
Mine was 46 two Novembers in a row
Considering I live in the pacific northwest, I was pleasantly surprised yet so plan to supplement a little this winter (combined with vitamin k2).
My 12 year old was only at 29! 😭
We're working on it
My cancer patients and I each take 14,000 units per day in the sunny Phoenix area.
I've seen estimates that 1000 IU raises D about 10. Apparently there's a saturation level, else yours should be about 140, which I'm guessing it's not. The studies you provided indicate about 55 is the optimum for general infection, and seems to make covid infection low probability.
I get tested twice a year and I range 50-75 with 4000 IU. I'm in a sunny southern latitude too, but my sun exposure is mostly walking to and from my car. I'm an astronomy hobbyist, but I don't think I get much D from starlight. Cancer concerns probably discourage a lot of people from too much sun exposure. But it really doesn't take a lot of sun to get a normal dose. Sunlight also damages DNA which decreases longevity. Lots of mysteries remain, but there are likely optimum balances yet to be discovered. I'm hoping objective measurements will provide me with data that will maximize my own lifestyle. Working so far.
Yes, yours is likely a more appropriate dose for the general population. Cancer is such a difficult hurdle to overcome, that we in my medical practice go further in dosing. I say we, although I never had cancer (where's some wood I can knock on), but I do the equipoise thing along with the patients.
I assume your equipoise reference is seeking some sort of equilibrium, not the steroid. I've read we can't really overdose, but it seems likely there's a saturation point somewhere. I've heard healthy skin can produce up to 25,000 per day. Maybe that's for surfers or nudists? Or our evolutionary ancestors? Maybe we were designed for higher levels than we typically see these days. I'm wondering if I'm a slacker for accepting readings in the 50s, with "only" 4000 IU supplement.
I like vitamin D levels between 70 and 100, but this fat-soluble vitamin doesn't hang around enough in the blood for adequate test reliability
Supplements are cheap and I haven't heard of any ill effects.
You never disappoint. Great read. Forwarded to several folks
I saw this article and didn't have time to read it when you published it, but I came back to it and am glad I did. I think I just got more information on the immune system in the last fifteen minutes than anyone has provided me in a year. Thank you!
Very helpful overview. I’ve been waiting for this kind of summary for a long time. Thank you for providing it. Very well written.
Just now read your article, thank you ! written so that a non-biology-student can understand too.
Great article - very informative. Do you have any views on the Novavax vaccine? We are about to get it in Australia where I am located. Do you think it will have a similar potential for heart damage or is likely to be safer? It would be great to get your thoughts.
I would personally refuse any of these vaccines. The benefit / risk ratio is either zero or negative. Covid has a 99.85% survival rate.
Yes - I agree but in my state it looks like I won’t be able to go into shops for 12 months and potentially not work unless I get one of the vaccines. I would prefer to get none of them and I really resent it being forced upon me but I may have to get it - was hoping novavax was a less harmful option?
My family chose to uproot and move across the US a few decades ago for the main reason that we are a non-vaccinating lineage, and vax exemptions are stronger in Arizona than elsewhere in the US. I would definitely do it again if I had to. So I'm probably not the best person to ask that particular question.